Computational Medicinal Chemistry for Drug Discovery

An overview of the book: Computational Medicinal Chemistry for Drug Discovery

Patrick Bultinck ,  Hans De Winter,  Wilfried Langenaeker,  Jan Tollenare
Observing computational chemistry's proven value to the introduction of new medicines, this reference offers the techniques most frequently utilized by industry and academia for ligand design. Featuring contributions from more than fifty pre-eminent scientists, Computational Medicinal Chemistry for Drug Discovery surveys molecular structure computation, intermolecular behavior, ligand-receptor interaction, and modeling responding to market demands in its selection and authoritative treatment of topics. The book examines molecular mechanics, semi-empirical methods, wave function-based quantum chemistry, density functional theory, 3-D structure generation, and hybrid methods.

Directory of Approved Biopharmaceutical Products

A brief overview of the book

Directory of Approved Biopharmaceutical Products

# Provides a brief overview of each biopharmaceutical approved in the US and by centralized European drug approval system in the EU
# Outlines the properties of each drug in consistent monograph format
# Includes information from both regulatory agencies and pharmaceutical companies
# Indexes drugs both by brand name and by biological activity

Biopharmaceuticals, the term for genetically engineered therapeutic proteins, monoclonal antibodies, and nucleic acid-based products, have become an increasing part of the pharmaceutical armament. While this category of drugs accounts for approximately 25% of all new drugs coming to market, very few references exist that review these commercially available products. Until now, accessing data on the list of currently approved biopharmaceuticals has been laborious and patchy.

Directory of Approved Biopharmaceutical Products brings together key information on various aspects of these compounds, presenting a brief summary of each biopharmaceutical currently approved for medical use. Each summary includes the scientific and trade name, year and regions approved, approved indications, manufacturer, marketing right, method of manufacture, scientific overview, and therapeutic properties. Based on information gathered from regulatory agencies and pharmaceutical manufacturers, the book presents the most comprehensive data currently available in a single, convenient volume.

This comprehensive and consistent approach will save professionals in the pharmaceutical industry hours spent trawling the literature - and provides a singular resource for future reference.

Publication Date   September 2004
Publisher   CRC Press
Product Type   Book
Pages   336
ISBN Number   0415263689
Product Code   CRC007